Hebade, Madhav J. Kamble, Rahul D. Hese, Shrikant V. Mogle, Pratima P. Ambhore, Ajay N. Kadam, Shuddhodan N. Dawane, Bhaskar S. A rapid, mild, and efficient method for C-5 iodination/thiocyanation of 2-aminothiazoles <p>An efficient, green, rapid multitasking protocol for the selective C-5 substitution of 2-aminothiazole using iodic acid and aqueous PEG-400 was developed. The method found suitable for C-5 substitution i.e. iodination and thiocyanation of 2-amino thiazole using iodine and ammonium thiocyanate respectively. Iodic acid was found to be a good oxidant and aqueous PEG-400 as green reaction solvent.</p> Aq. PEG-400;iodination;thiocyanation;iodic acid;2-aminothiazole 2016-06-24
    https://tandf.figshare.com/articles/journal_contribution/A_rapid_mild_and_efficient_method_for_C-5_iodination_thiocyanation_of_2-aminothiazoles/3462917
10.6084/m9.figshare.3462917.v1