TY - DATA T1 - Nuclear Magnetic Resonance (NMR) Spectra of different compounds PY - 2016/07/11 AU - SHAHZAD Riaz AU - George Weaver UR - https://repository.lboro.ac.uk/articles/figure/Nuclear_Magnetic_Resonance_NMR_Spectra_of_different_compounds/3458771 DO - 10.17028/rd.lboro.3458771.v1 L4 - https://ndownloader.figshare.com/files/5436491 L4 - https://ndownloader.figshare.com/files/5436494 L4 - https://ndownloader.figshare.com/files/5436497 L4 - https://ndownloader.figshare.com/files/5436500 L4 - https://ndownloader.figshare.com/files/5436503 L4 - https://ndownloader.figshare.com/files/5436506 L4 - https://ndownloader.figshare.com/files/5436509 L4 - https://ndownloader.figshare.com/files/5436512 L4 - https://ndownloader.figshare.com/files/5436515 L4 - https://ndownloader.figshare.com/files/5436518 L4 - https://ndownloader.figshare.com/files/5436521 L4 - https://ndownloader.figshare.com/files/5436524 L4 - https://ndownloader.figshare.com/files/5436527 L4 - https://ndownloader.figshare.com/files/5436530 L4 - https://ndownloader.figshare.com/files/5436533 L4 - https://ndownloader.figshare.com/files/5436536 L4 - https://ndownloader.figshare.com/files/5436539 L4 - https://ndownloader.figshare.com/files/5436542 L4 - https://ndownloader.figshare.com/files/5436545 L4 - https://ndownloader.figshare.com/files/5436551 L4 - https://ndownloader.figshare.com/files/5436554 L4 - https://ndownloader.figshare.com/files/5436557 L4 - https://ndownloader.figshare.com/files/5436560 L4 - https://ndownloader.figshare.com/files/5436563 L4 - https://ndownloader.figshare.com/files/5436566 L4 - https://ndownloader.figshare.com/files/5436569 L4 - https://ndownloader.figshare.com/files/5436572 L4 - https://ndownloader.figshare.com/files/5436575 L4 - https://ndownloader.figshare.com/files/5436578 L4 - https://ndownloader.figshare.com/files/5436581 L4 - https://ndownloader.figshare.com/files/5436584 L4 - https://ndownloader.figshare.com/files/5436587 L4 - https://ndownloader.figshare.com/files/5436590 L4 - https://ndownloader.figshare.com/files/5436596 L4 - https://ndownloader.figshare.com/files/5436599 L4 - https://ndownloader.figshare.com/files/5436602 L4 - https://ndownloader.figshare.com/files/5436605 L4 - https://ndownloader.figshare.com/files/5436608 L4 - https://ndownloader.figshare.com/files/5436611 L4 - https://ndownloader.figshare.com/files/5436614 L4 - https://ndownloader.figshare.com/files/5436617 L4 - https://ndownloader.figshare.com/files/5436620 KW - NMR data sets KW - Fluorine KW - Heterocycles KW - Perfluoroarenes KW - SNAr KW - Cyclisation KW - Aromatic KW - Organic Chemistry N2 - NMR spectra of the different compounds in Shahzad, Riaz. Thesis 2016: https://hdl.handle.net/2134/21790Thesis abstract: The reactivity of perfluoroarenes and hetarenes towards SNAr reactions was studied as part of a synthetic programme to form an assembly of novel heterocyclic aromatic compounds for material and pharmaceutical applications. In chapter 1 the chemistry of perfluoroarenes is reviewed together with the use of conjugated compounds in organo-electronic applications. In chapter 2 the successful replacement of the remaining fluorine atoms in 6,12-difluorobenzo[1,2-b:4,5-b']bis[b]benzothiophene through SNAr reaction with long chain alkoxy and alkylthio nucleophiles is reported. An X-ray crystallographic investigation into their solid state packing was undertaken which would provide useful information for organoelectronic applications. Reactions with nitrogen and carbon based nucleophiles were also studied but met with little success. In chapter 3, alternative methods for the reductive cyclization of aryl and 2-bromoaryl perfluoroethers and sulfides to replace the currently used lithium-bromine exchange were explored, namely the use of radical cyclizations, palladium, magnesium, copper and Rieke metals. Some success was found using magnesium as a reagent although yields were low. Attempts to effect cyclisation reactions by ortho-lithiation and Ullmann coupling reaction with fluoroarenes is also reported. In chapter 4 attempts to generate alternative ring fusion in annulation reactions to form fused benzothiophenes by a dianion strategy are described. Development of methods to synthesise helicene or curved polycyclic structures from dibenzothiophene precursors is reported. In chapter 5 the synthesis of nitrogen containing fluorinated compounds with potential bioactivity is described. A series of novel amino substituted fluoroaromatics were successfully synthesised by adding different nitrogen based nucleophiles to pentafluoropyridine. Smiles rearrangement of a tetrafluoropyridyl sulphonamide was found to occur. A number of fluoropyridyl aniline derivatives were successfully synthesised some of which were submitted for biological screening. Substitution reactions of bis-nucleophiles bearing two heteroatom groups to form fused six membered rings were also studied. A Smiles rearrangement was identified in the reaction with an aminobenzenethiolate and confirmed by X-ray crystallography. Experimental procedures are given in chapter 6 as well as characterisation and crystallographic data of molecules synthesised during the research. ER -