10.1371/journal.pone.0157418.g002 Benjamin R. Lin Benjamin R. Lin Derek J. Le Derek J. Le Yabin Chen Yabin Chen Qiwei Wang Qiwei Wang D. Doug Chung D. Doug Chung Ricardo F. Frausto Ricardo F. Frausto Christopher Croasdale Christopher Croasdale Richard W. Yee Richard W. Yee Fielding J. Hejtmancik Fielding J. Hejtmancik Anthony J. Aldave Anthony J. Aldave Clinical features of chromosome 10q23-q24 linked dystrophy. Public Library of Science 2016 COL 17A COL 17A variant segregates dynamin binding protein SNV XVII Epithelial Recurrent Erosion Dystrophy splice donor site gene silico analysis Segregation Analysis Confirms DNA DNMBP dystrophy Whole Exome Sequencing COL 17A mutation c .3156C variant family members 2016-06-16 06:01:04 Figure https://plos.figshare.com/articles/figure/Clinical_features_of_chromosome_10q23-q24_linked_dystrophy_/3449771 <p>A. Affected individual V-2 (28 years old) demonstrates a clear cornea in the right eye. B. Three months later, she developed a corneal erosion (arrows). C. Affected individual V-3 (24 years old) also demonstrated clear corneas prior to the development of a corneal erosion, the location of which can be identified by the opacification of the corneal epithelium (arrows). D. Affected individual IV-1 (72 years old) demonstrates diffuse subepithelial opacification secondary to chronic recurrent corneal erosions seen with slit and diffuse illumination in the right (D and E) and left (F) eyes.</p>