10.1021/acs.joc.6b00643.s001 Weiming Hu Weiming Hu Song Sun Song Sun Jiang Cheng Jiang Cheng Formal [3 + 2] Reaction of α,α-Diaryl Allylic Alcohols with <i>sec</i>-Alcohols: Proceeding with Sequential Radical Addition/Migration toward 2,3-Dihydrofurans Bearing Quaternary Carbon Centers American Chemical Society 2016 sec migration electron density access oxaspiro compounds dehydration process cyclic reactions group tolerance novel method aryl 2016-05-02 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Formal_3_2_Reaction_of_Diaryl_Allylic_Alcohols_with_i_sec_i_Alcohols_Proceeding_with_Sequential_Radical_Addition_Migration_toward_2_3_Dihydrofurans_Bearing_Quaternary_Carbon_Centers/3369898 An unprecedented TBHP-promoted formal [3 + 2] annulation of <i>sec</i>-alcohols with α,α-diaryl allylic alcohols has been developed, leading to 2,3-dihydrofurans in moderate to excellent yields with good functional group tolerance. This procedure involves sequential radical addition, 1,2-aryl migration, and a dehydration process, where the migration of aryl with lower electron density is favored. Notably, cyclic reactions with <i>sec</i>-alcohols also ran smoothly, providing a novel method to access oxaspiro compounds.