10.1021/ja031806c.s002
Emily C. Carson
Emily C.
Carson
Stephen J. Lippard
Stephen J.
Lippard
Oxidation of Sulfide, Phosphine, and Benzyl Substrates Tethered to N-Donor
Pyridine Ligands in Carboxylate-Bridged Diiron(II) Complexes
American Chemical Society
2004
toluene monooxygenase
Benzyl Substrates Tethered
Fe 2
methane monooxygenase
Complexe
ligand oxidation
compound
O 2 CAr Tol
Ar Tol
multicomponent monooxygenases
2004-03-24 00:00:00
Dataset
https://acs.figshare.com/articles/dataset/Oxidation_of_Sulfide_Phosphine_and_Benzyl_Substrates_Tethered_to_N_Donor_Pyridine_Ligands_in_Carboxylate_Bridged_Diiron_II_Complexes/3345157
Substituted pyridines were employed to prepare a series of terphenylcarboxylate-bridged diiron(II) compounds to mimic aspects of the chemistry at the active sites of bacterial multicomponent monooxygenases, including soluble methane monooxygenase (sMMO) and toluene monooxygenase (ToMO). Complexes of general formula [Fe<sub>2</sub>(O<sub>2</sub>CAr<sup>Tol</sup>)<sub>4</sub>L], L = 2, 3, or 4-pyridyldiphenylphosphine, 2-pyridylphenylsulfide, or 2-benzylpyridine and Ar<sup>Tol</sup> = 2,6-di(<i>p</i>-tolyl)benzoate, were synthesized and characterized by X-ray crystallography. Upon exposure of these compounds to dioxygen, ligand oxidation ensued and, in one case, proceeded catalytically.