10.1371/journal.pone.0033844.g003
Joachim Silber
Joachim
Silber
Anders Jacobsen
Anders
Jacobsen
Tatsuya Ozawa
Tatsuya
Ozawa
Girish Harinath
Girish
Harinath
Alicia Pedraza
Alicia
Pedraza
Chris Sander
Chris
Sander
Eric C. Holland
Eric C.
Holland
Jason T. Huse
Jason
T. Huse
miR-34a induces cell cycle arrest and inhibits tumorigenesis in proneural GBM cells.
Public Library of Science
2012
induces
inhibits
tumorigenesis
proneural
gbm
2012-03-27 00:54:03
Figure
https://plos.figshare.com/articles/figure/_miR_34a_induces_cell_cycle_arrest_and_inhibits_tumorigenesis_in_proneural_GBM_cells_/333243
<p><b>A</b>) 48 hours post-transfection, proneural TS543 were pulsed with BrdU and assayed for cell cycle distribution and <b>B</b>) apoptosis by Annexin V flow cytometry. Staurosporine was added as positive control. <b>C</b>) <i>Ex vivo</i>-transfected TS453 cells stably expressing a luciferase reporter plasmid were xenografted into the brains of ICR scid mice and tumor formation and growth was followed over 11 days. Error bars represent standard deviation within a single experimental set containing multiple replicates. Similar results were obtained in at least 3 independent experiments. *, P<0.05. **, P<0.005.</p>