Patil, Nitin T. Yamamoto, Yoshinori Formation of a Quaternary Carbon Center through the Pd(0)/PhCOOH-Catalyzed Allylation of Cyclic β-Keto Esters and 1,3-Diketones with Alkynes Formation of a quaternary carbon center through the allylation of β-keto esters and 1,3-diketones with alkynes is accomplished by the use of Pd(0)/benzoic acid catalyst. Reactions of various cyclic β-keto esters and 1,3-diketones with alkynes in the presence of Pd<sub>2</sub>dba<sub>3</sub>·CHCl<sub>3</sub> (5 mol %), PPh<sub>3</sub> (40 mol %), and PhCOOH (10 mol %) proceeded at 100 °C in toluene (5 M) to give the corresponding allylation products in high yields in a regio- and stereoselective manner. The possibility of asymmetric allylation is also discussed. esters;Pd;allylation products;mol;diketone;quaternary carbon center;stereoselective manner;Quaternary Carbon Center;keto;alkyne;Alkynes Formation 2004-09-17
    https://acs.figshare.com/articles/journal_contribution/Formation_of_a_Quaternary_Carbon_Center_through_the_Pd_0_PhCOOH_Catalyzed_Allylation_of_Cyclic_Keto_Esters_and_1_3_Diketones_with_Alkynes/3324643
10.1021/jo0490144.s001