10.1021/jo048985g.s001
Yohan Georges
Yohan
Georges
Yves Allenbach
Yves
Allenbach
Xavier Ariza
Xavier
Ariza
Jean-Marc Campagne
Jean-Marc
Campagne
Jordi Garcia
Jordi
Garcia
An Efficient, Stereoselective Approach to
<i>s</i><i>yn</i>-1,2-Diols Protected as Cyclic
Carbonates
American Chemical Society
2004
Stereoselective Approach
cyclic carbonates
benzoate analogues
2004-10-15 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/An_Efficient_Stereoselective_Approach_to_i_s_i_i_yn_i_1_2_Diols_Protected_as_Cyclic_Carbonates/3320548
Enantioenriched 4-hydroxyalk-2-ynyl carbonates
(or benzoates) have been prepared by stereoselective zinc-mediated addition of alkyl 2-propynyl carbonates (or their
benzoate analogues) to aldehydes. Their partial reduction
to <i>Z</i>-olefins followed by cyclization under mild Pd-catalyzed
conditions allowed a straightforward access to enantioenriched <i>syn</i>-1,2-diols protected as cyclic carbonates.