%0 Journal Article
%A Mazik, Monika
%A Radunz, Wolfgang
%A Boese, Roland
%D 2004
%T Molecular Recognition of Carbohydrates with Acyclic
Pyridine-Based Receptors
%U https://acs.figshare.com/articles/journal_contribution/Molecular_Recognition_of_Carbohydrates_with_Acyclic_Pyridine_Based_Receptors/3318493
%R 10.1021/jo048979k.s006
%2 https://ndownloader.figshare.com/files/5157259
%K recognition capabilities
%K monosaccharide
%K β vs α binding selectivity
%K recognition group
%K buildings blocks
%K Molecular Recognition
%K binding properties
%K Amidopyridine receptors
%K spacer subunits
%K Aminopyridine receptors
%X The recognition capabilities of acyclic pyridine-based receptors toward monosaccharides were
evaluated. Aminopyridine receptors based on the 2,4,6-trimethyl- or 2,4,6-triethylbenzene frame
show high β vs α binding selectivity in the recognition of glucopyranosides. Amidopyridine receptors,
which are sterically less hindered at nitrogen, display high efficiency and an inverse selectivity.
The 2-aminopyridine group has been established as a highly effective recognition group in the
binding of monosaccharides. The factors influencing the binding properties of receptors 1−15, which
differ in the nature and number of binding and spacer subunits used as the buildings blocks, are
discussed.
%I ACS Publications