Surfactant-Assisted Synthesis of
Water-Soluble and Biocompatible
Semiconductor Quantum Dot Micelles
Hongyou Fan
Erik W. Leve
Chessa Scullin
John Gabaldon
David Tallant
Scott Bunge
Tim Boyle
Michael C. Wilson
C. Jeffrey Brinker
10.1021/nl050017l.s001
https://acs.figshare.com/articles/journal_contribution/Surfactant_Assisted_Synthesis_of_Water_Soluble_and_Biocompatible_Semiconductor_Quantum_Dot_Micelles/3291790
We report a simple, rapid approach to synthesize water-soluble and biocompatible fluorescent quantum dot (QD) micelles by encapsulation
of monodisperse, hydrophobic QDs within surfactant/lipid micelles. Analyses of UV−vis and photo luminescence spectra, along with transmission
electron microscopy, indicate that the water-soluble semiconductor QD micelles are monodisperse and retain the optical properties of the
original hydrophobic QDs. The QD micelles were shown to be biocompatible and exhibited little or no aggregation when taken up by cultured
rat hippocampal neurons.
2005-04-13 00:00:00
transmission electron microscopy
rat hippocampal neurons
photo luminescence spectra
Biocompatible Semiconductor Quantum Dot Micelles
quantum dot
QD micelles
biocompatible
UV
semiconductor QD micelles