Delayed toxicity of rats following LeTx challenge with RDI-IgG1 and RDI-IgG2 fusion proteins.
Diane Thomas
John Naughton
Christopher Cote
Susan Welkos
Marianne Manchester
John A. T. Young
10.1371/journal.pone.0034611.g007
https://plos.figshare.com/articles/figure/_Delayed_toxicity_of_rats_following_LeTx_challenge_with_RDI_IgG1_and_RDI_IgG2_fusion_proteins_/325688
<p>Male 200 gram HSD rats (5/group) were co-injected i.v. with LeTx (40 µg PA+12 µg LF) and either 19 µg of RDI; or 49 µg of either RDI-eIgG1, RDI-IgG1, or RDI-IgG2. Rats were monitored and time of death recorded.</p>
2013-02-20 06:38:39
toxicity
rats
letx
rdi-igg1
rdi-igg2
fusion