10.1021/ja057741q.s001
Yike Ni
Yike
Ni
John Montgomery
John
Montgomery
Synthetic Studies and Mechanistic Insight in Nickel-Catalyzed
[4+2+1] Cycloadditions
American Chemical Society
2006
sequence
divinylcyclopropane
evidence
diene
cycloaddition
Stereochemical studies
mechanism
stereoselectivitie
trimethylsilyl
substrate
alkyne
Synthetic Studies
sigmatropic
rearrangement
Mechanistic Insight
Cycloaddition
procedure
2006-03-01 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Synthetic_Studies_and_Mechanistic_Insight_in_Nickel_Catalyzed_4_2_1_Cycloadditions/3235945
A new nickel-catalyzed procedure for the [4+2+1] cycloaddition of (trimethylsilyl)diazomethane
with alkynes tethered to dienes has been developed. A broad range of unsaturated substrates participate
in the sequence, and stereoselectivities are generally excellent. Stereochemical studies provided evidence
for a mechanism that involves the [3,3] sigmatropic rearrangement of divinylcyclopropanes.