TY - DATA T1 - PDGFRβ Is a Novel Marker of Stromal Activation in Oral Squamous Cell Carcinomas - Fig 5 PY - 2016/04/29 AU - Vinay K. Kartha AU - Lukasz Stawski AU - Rong Han AU - Paul Haines AU - George Gallagher AU - Vikki Noonan AU - Maria Kukuruzinska AU - Stefano Monti AU - Maria Trojanowska UR - https://plos.figshare.com/articles/figure/PDGFR_Is_a_Novel_Marker_of_Stromal_Activation_in_Oral_Squamous_Cell_Carcinomas_-_Fig_5/3212737 DO - 10.1371/journal.pone.0154645.g005 L4 - https://ndownloader.figshare.com/files/5043388 KW - cell carcinoma KW - OSCC KW - reference collagen expression KW - 3A KW - CAF markers KW - cancer genome atlas KW - PDGFR KW - tumor KW - Oral Squamous Cell Carcinomas Carcinoma KW - fibroblast surface markers KW - TCGA cancer datasets KW - candidate CAF markers KW - novel approach KW - collagens COL 1A COL 1A KW - 11 cancer types N2 - Pan-cancer NN analysis highlights PDGFRβ as a potential CAF marker in multiple cancer types A. Heatmap of average pairwise Kolmogorov-Smirnoff (KS) D statistics using the top 50 genes in the collagen NN cancer analysis of each of 11 cancer types. B. Venn diagram of top 50 genes in collagen NN ranked list within the five most closely related cancers (based on the average KS D statistic; Fig 5A). Core overlap has 11 genes, which includes PDGFRβ, highlighted in red. ACC: Adrenocortical carcinoma; BLCA: Bladder urothelial carcinoma; COAD: Colon adenocarcinoma; KIRC: Kidney renal clear cell carcinoma; LAML: Acute myeloid leukemia; LIHC: Liver hepatocellular carcinoma; LUAD: Lung adenocarcinoma; LUSC: Lung squamous cell carcinoma; PAAD: Pancreatic adenocarcinoma; PRAD: Prostate adenocarcinoma. ER -