TY - DATA T1 - Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones PY - 2016/04/21 AU - Sheng-Ying Hsieh AU - Jeffrey W. Bode UR - https://acs.figshare.com/articles/journal_contribution/Silicon_Amine_Reagents_for_the_Photocatalytic_Synthesis_of_Piperazines_from_Aldehydes_and_Ketones/3188005 DO - 10.1021/acs.orglett.6b00722.s001 L4 - https://ndownloader.figshare.com/files/4989046 KW - silicon Amine Reagents KW - tin amine protocol KW - aliphatic aldehydes KW - Photocatalytic Synthesis KW - piperazine KW - SLAP reagents KW - form N KW - Ketones Silicon amine protocol N2 - Silicon amine protocol (SLAP) reagents for photocatalytic cross-coupling with aldehydes and ketones to form N-unprotected piperazines have been developed. This blue light promoted process tolerates a wide range of heteroaromatic, aromatic, and aliphatic aldehydes and structurally and stereochemically complex SLAP reagents. It provides a tin-free alternative to SnAP (tin amine protocol) reagents for the synthesis of substituted piperazines. ER -