%0 Figure %A Jiang, Feng %A Zhou, Xiangyu %A Huang, Jing %D 2016 %T Knockdown of lncRNA-ROR reversed hypertrophic responses of cardiomyocytes. %U https://plos.figshare.com/articles/figure/Knockdown_of_lncRNA_ROR_reversed_hypertrophic_responses_of_cardiomyocytes_/3183043 %R 10.1371/journal.pone.0152767.g003 %2 https://ndownloader.figshare.com/files/4966999 %K hypertrophic heart %K Long %K Cardiac Hypertrophy Background Cardiac hypertrophy %K diseases results %K miR %K cardiomyocytes subject %K heart failure %K role %K novel antihypertrophic therapeutics %K novel therapies %K BNP %K phenylephrine treatment %K hypertrophic responses %K RNA %K ANP %K expression %X

(A) After the transfection of ROR-specific siRNA, the mRNA expression of lncRNA-ROR was dramatically decreased compared with the control siRNA-transfected cells. (B) The enlarged cardiomyocytes induced by PE treatment was attenuated by the transfection of lncRNA-ROR. The mRNA (C) and protein (D) expression levels of ANP and BNP were decreased after the knockdown of lncRNA-ROR. * p<0.05, ** p<0.01 compared with control siRNA-treated cells.

%I PLOS ONE