%0 Figure %A M. Sequeira, Jeffrey %A Desai, Ankuri %A I. Berrocal-Zaragoza, Maria %A M. Murphy, Michelle %A D. Fernandez-Ballart, Joan %A V. Quadros, Edward %D 2016 %T Place avoidance parameters in SC and GST-PRW rats. %U https://plos.figshare.com/articles/figure/Place_avoidance_parameters_in_SC_and_GST_PRW_rats_/3140104 %R 10.1371/journal.pone.0152249.g004 %2 https://ndownloader.figshare.com/files/4882357 %K place avoidance tasks %K GST %K PRW %K gestation %K novel object recognition task %K place avoidance task %K FR %K neurodevelopmental disorders %K Severe Behavioral Deficits %K Ab %K tube defect pregnancy %K Folate Receptor Alpha Antibodies %K POW %X

Passive and active place avoidance parameters in different trials for normal rabbit IgG exposed rats (-●-; SC group; n = 8) and GST-PRW rats exposed to FRα Ab (-○-; GST-PRW group; n = 6). Inability of the GST-PRW rats to learn the passive place avoidance (Panels A and B) and the active place avoidance (Panels C and D) is evident from the lack of a decrease in number of entrances and the shocks received along with lack of a decrease in time to first entry in subsequent trials. Median values for each parameter are reported. *Different from the SC group (P < 0.05). †The first trial (in the control group) was different from the rest of the trials (P < 0.05). Bonferroni correction was applied to the P values for multiple comparisons.

%I PLOS ONE