Changes in poisoning deaths involving co-proxamol, other analgesics, and all drugs, in England and Wales, 1998–2010, associated with the Committee on Safety of Medicines (CSM) announcement in January 2005.
Keith Hawton
Helen Bergen
Sue Simkin
Claudia Wells
Navneet Kapur
David Gunnell
10.1371/journal.pmed.1001213.t003
https://plos.figshare.com/articles/dataset/_Changes_in_poisoning_deaths_involving_co_proxamol_other_analgesics_and_all_drugs_in_England_and_Wales_1998_8211_2010_associated_with_the_Committee_on_Safety_of_Medicines_CSM_announcement_in_January_2005_/311936
a<p>Using interrupted time-series segmented regression analysis where the intervention point is taken as the end of 2004 (the CSM announcement on the withdrawal of co-proxamol, January 2005).</p>b<p>Estimated for the midpoint quarter of 2005–2010. See <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001213#pmed.1001213.s002" target="_blank">Text S1</a> for method, equation (2) or (3).</p>c<p>Absolute difference of estimated number with CSM announcement and estimated number without CSM announcement, taken at the mid-point of the post-intervention period, see <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001213#pmed.1001213.s002" target="_blank">Text S1</a> equation (4).</p>d<p>95% CIs taken from Stata results or calculated according to Zhang et al. <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001213#pmed.1001213-Zhang1" target="_blank">[38]</a>.</p>e<p>Other analgesics include: co-codamol, codeine, co-dydramol, dihydrocodeine, NSAIDS, paracetamol, and tramadol.</p>
2012-05-08 00:32:16
poisoning
deaths
involving
england
medicines
january