More, Atul A. Ramana, Chepuri V. Total Synthesis of Integrastatin B Enabled by a Benzofuran Oxidative Dearomatization Cascade The first total synthesis of integrastatin B, a potent HIV-1 integrase inhibitor, has been accomplished in seven steps with a 17.9% overall yield employing easily accessible starting compounds. The Oxone-mediated oxidative benzofuran dearomatization cascade has been employed as the key skeletal construct to forge the central tetracyclic nucleus. integrastatin B;tetracyclic nucleus;dearomatization;Integrastatin B Enabled;HIV;Benzofuran Oxidative Dearomatization Cascade;benzofuran;synthesis;compound;oxidative;Total Synthesis;integrase inhibitor;cascade 2016-03-07
    https://acs.figshare.com/articles/dataset/Total_Synthesis_of_Integrastatin_B_Enabled_by_a_Benzofuran_Oxidative_Dearomatization_Cascade/3085354
10.1021/acs.orglett.6b00404.s002