%0 Generic
%A Samaroo, Diana
%A Soll, Clifford E.
%A Todaro, Louis J.
%A Drain, Charles M.
%D 2006
%T Efficient Microwave-Assisted Synthesis
of Amine-Substituted
Tetrakis(pentafluorophenyl)porphyrin
%U https://acs.figshare.com/articles/dataset/Efficient_Microwave_Assisted_Synthesis_of_Amine_Substituted_Tetrakis_pentafluorophenyl_porphyrin/3051619
%R 10.1021/ol060946z.s001
%2 https://ndownloader.figshare.com/files/4757245
%K Tetraki
%K Efficient
%K displacement
%K TPPF 20
%K tetraki
%K application
%K platform
%K derivative
%K method
%K synthesis
%K amines
%K formation
%K microwave irradiation
%K yield
%K porphyrin conjugates
%K Synthesi
%X We report an efficient and rapid means for the synthesis of tetrakis(pentafluorophenyl)porphyrin (TPPF20) derivatives by microwave irradiation
in an environmentally acceptable solvent. The selective displacement of the para-fluorine groups in TPPF20 by primary amines occurs in yields
between 70 and 95%. This method demonstrates that TPPF20 is an ideal platform for the rapid formation of porphyrin conjugates for therapeutic,
catalytic, and other applications.
%I ACS Publications