%0 Generic %A Samaroo, Diana %A Soll, Clifford E. %A Todaro, Louis J. %A Drain, Charles M. %D 2006 %T Efficient Microwave-Assisted Synthesis of Amine-Substituted Tetrakis(pentafluorophenyl)porphyrin %U https://acs.figshare.com/articles/dataset/Efficient_Microwave_Assisted_Synthesis_of_Amine_Substituted_Tetrakis_pentafluorophenyl_porphyrin/3051619 %R 10.1021/ol060946z.s001 %2 https://ndownloader.figshare.com/files/4757245 %K Tetraki %K Efficient %K displacement %K TPPF 20 %K tetraki %K application %K platform %K derivative %K method %K synthesis %K amines %K formation %K microwave irradiation %K yield %K porphyrin conjugates %K Synthesi %X We report an efficient and rapid means for the synthesis of tetrakis(pentafluorophenyl)porphyrin (TPPF20) derivatives by microwave irradiation in an environmentally acceptable solvent. The selective displacement of the para-fluorine groups in TPPF20 by primary amines occurs in yields between 70 and 95%. This method demonstrates that TPPF20 is an ideal platform for the rapid formation of porphyrin conjugates for therapeutic, catalytic, and other applications. %I ACS Publications