TY - DATA T1 - Efficient Microwave-Assisted Synthesis of Amine-Substituted Tetrakis(pentafluorophenyl)porphyrin PY - 2006/10/26 AU - Diana Samaroo AU - Clifford E. Soll AU - Louis J. Todaro AU - Charles M. Drain UR - https://acs.figshare.com/articles/journal_contribution/Efficient_Microwave_Assisted_Synthesis_of_Amine_Substituted_Tetrakis_pentafluorophenyl_porphyrin/3051613 DO - 10.1021/ol060946z.s002 L4 - https://ndownloader.figshare.com/files/4757239 KW - Tetraki KW - Efficient KW - displacement KW - TPPF 20 KW - tetraki KW - application KW - platform KW - derivative KW - method KW - synthesis KW - amines KW - formation KW - microwave irradiation KW - yield KW - porphyrin conjugates KW - Synthesi N2 - We report an efficient and rapid means for the synthesis of tetrakis(pentafluorophenyl)porphyrin (TPPF20) derivatives by microwave irradiation in an environmentally acceptable solvent. The selective displacement of the para-fluorine groups in TPPF20 by primary amines occurs in yields between 70 and 95%. This method demonstrates that TPPF20 is an ideal platform for the rapid formation of porphyrin conjugates for therapeutic, catalytic, and other applications. ER -