TY - DATA T1 - DNA-Catalyzed Transfer of a Reporter Group PY - 2006/12/13 AU - Tom N. Grossmann AU - Oliver Seitz UR - https://acs.figshare.com/articles/journal_contribution/DNA_Catalyzed_Transfer_of_a_Reporter_Group/3041818 DO - 10.1021/ja0670097.s001 L4 - https://ndownloader.figshare.com/files/4745413 KW - rhodamine dye KW - Transfer KW - detection KW - manner KW - acid KW - transfer KW - fluorescein dye KW - turnover numbers KW - emission KW - Dabcyl group KW - reporter group KW - setup KW - Reporter GroupHerein KW - PNA N2 - Herein we describe a novel DNA-catalyzed transfer of a reporter group from a donating to an accepting oligo-peptide nucleic acid (PNA), generating high catalytic turnover numbers in a DNA-sequence specific manner. The demonstrated transfer of the Dabcyl group was designed to switch on emission of a fluorescein dye while switching off emission of a rhodamine dye. This setup allows the highly sensitive and selective detection of DNA-sequences in real time. ER -