%0 Generic %A Mebi, Charles A. %A Nair, Radhika P. %A Frost, Brian J. %D 2007 %T pH-Dependent Selective Transfer Hydrogenation of α,β-Unsaturated Carbonyls in Aqueous Media Utilizing Half-Sandwich Ruthenium(II) Complexes %U https://acs.figshare.com/articles/dataset/pH_Dependent_Selective_Transfer_Hydrogenation_of_Unsaturated_Carbonyls_in_Aqueous_Media_Utilizing_Half_Sandwich_Ruthenium_II_Complexes/3033352 %R 10.1021/om060892x.s008 %2 https://ndownloader.figshare.com/files/4735990 %K PPh 3 %K multinuclear NMR spectroscopy %K carbonyl functionality %K regioselective transfer hydrogenation %K PR 3 %K HCOOH %K transfer hydrogenation %K IndRu %K benzylidene acetone %K PTA %K phosphine compounds %K compounds exhibit piano stool geometries %K CD 3OD %K ruthenium hydrides %K Transfer Hydrogenation %K hydrogen source %K C 9H Ind %K Cp %K complex %K acidic solutions %K exhibit activity %K C 8H Dp %K dihydropentalenyl moieties %X Half-sandwich ruthenium(II) PTA complexes bearing the 1,2-dihydropentalenyl (C8H9-, Dp) and indenyl (C9H7-, Ind) ancillary ligands have been synthesized and characterized using multinuclear NMR spectroscopy and X-ray crystallography. The complexes DpRu(PTA)(PPh3)Cl, DpRu(PTA)2Cl, IndRu(PTA)(PPh3)Cl, and [IndRu(PTA)2(PPh3)]Cl were obtained in good to excellent yields. The solid-state structures of these compounds exhibit piano stool geometries with η5-coordination of the indenyl and dihydropentalenyl moieties. DpRu(PTA)2Cl is water-soluble (S25°C = 43 mg/mL), while the mixed phosphine compounds are slightly soluble in acidic solutions. The Ru−H complexes, Cp‘Ru(PTA)(PPh3)H (Cp‘ = Ind, Cp), have been synthesized in good yield and spectroscopically and structurally characterized. The ruthenium hydrides undergo an H/D exchange reaction with CD3OD with relative rates CpRu(PTA)(PPh3)H ≫ IndRu(PTA)(PPh3)H > CpRu(PTA)2H. The air-stable Cp‘Ru(PTA)(PR3)Cl complexes (Cp‘ = Cp, Dp, Ind; PR3 = PPh3 or PTA) exhibit activity in the regioselective transfer hydrogenation of α,β-unsaturated carbonyls in aqueous media with HCOONa, HCOOH, or isopropanol/Na2CO3 serving as the hydrogen source. They were found to be effective in the selective reduction of the carbonyl functionality of cinnamaldehyde and the CC bond of benzylidene acetone and chalcone. IndRu(PTA)(PPh3)Cl was less active than Cp‘Ru(PTA)(PPh3)Cl (Cp‘ = Cp or Dp). Results of the transfer hydrogenation of unsaturated substrates using CpRu(PTA)(PPh3)H are also reported. %I ACS Publications