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Genome-wide chromatin and gene expression profiling during memory formation and maintenance in adult mice. [Data Record 6: RNA-seq]

Version 6 2016-06-30, 12:27
Version 5 2016-06-27, 12:21
Version 4 2016-04-23, 13:27
Version 3 2016-04-08, 13:42
Version 2 2016-04-03, 13:37
Version 1 2016-04-03, 12:58
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posted on 2016-06-30, 12:27 authored by Tonatiuh Pena CentenoTonatiuh Pena Centeno, orr shomroniorr shomroni, Magali Hennion, Rashi Halder, Ramon VidalRamon Vidal, Raza-Ur Rahman, Andre Fischer, Stefan Bonn
DESCRIPTION
Experiment type
- Expression profiling by high throughput sequencing
Design - Gene and exon expression changes in two distinct mouse brain regions (CA1, ACC) and three time-points (00H for naive, 01H for 1 hour, 04W for 4 weeks) before and after contextual learning (NAI for naive, CON for context, SHC for context shock).

DATA REPOSITORIES
EPIGENOME BROWSER (https://memory-epigenome-browser.dzne.de/)
Contains RNA-seq data under category "RNASEQ-DATA". Sample names include conditioning, time-point, tissue and replicate number (1 to 5; samples without numbers are merged replicates) separated by dashes. bigWig files can also be downloaded for local visualisation.
Gene Expression Omnibus (GEO)
Data is available on GEO under the accession number GSE74966 (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE74966), containing SRA and bigwig files to download for all 29 RNA-seq samples.

DATA GENERATION
Alignment and visualisation data was generate using the pre-processing code found in Figshare (https://dx.doi.org/10.6084/m9.figshare.3153193).

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