%0 Journal Article %A Miranda, Oscar R. %A You, Chang-Cheng %A Phillips, Ronnie %A Kim, Ik-Bum %A Ghosh, Partha S. %A H. F. Bunz, Uwe %A Rotello, Vincent M. %D 2007 %T Array-Based Sensing of Proteins Using Conjugated Polymers %U https://acs.figshare.com/articles/journal_contribution/Array_Based_Sensing_of_Proteins_Using_Conjugated_Polymers/2991490 %R 10.1021/ja0737927.s001 %2 https://ndownloader.figshare.com/files/4692364 %K polymer %K protein analytes %K 17 proteins %K fluorescence properties %K identification accuracy %K Conjugated PolymersA sensor array %K fluorescence response pattern %K protein samples %K Linear discriminant analyses %K micromolar concentrations %X A sensor array comprising six functionalized poly(p-phenyleneethynylene) polymers was constructed and used to detect and identify protein analytes. The presence of proteins alters the fluorescence properties of the polymers, generating a distinct fluorescence response pattern for a given protein. Linear discriminant analyses accurately differentiate the patterns of 17 proteins at nano- to micromolar concentrations. An identification accuracy of 97% was obtained on the basis of the tests with 68 unknown protein samples from the training set. %I ACS Publications