10.1021/jo8019797.s001 Bunpei Hatano Bunpei Hatano Keita Nagahashi Keita Nagahashi Tatsuro Kijima Tatsuro Kijima Zinc-Mediated Allylation and Alkylation of Aminals in the Presence of TMSCl and Diisopropylamine American Chemical Society 2008 diisopropylamine bromoacetate presence Alkylation bromonitrile Aminal Allylation alkylation reaction system Diisopropylamine allyl bromide benzyl bromide aminal TMSCl Presence butaverine organozinc reagents synthesis antispasmodic 2008-11-21 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Zinc_Mediated_Allylation_and_Alkylation_of_Aminals_in_the_Presence_of_TMSCl_and_Diisopropylamine/2898391 An alkylation of aminals with organozinc reagents derived from allyl bromide, benzyl bromide, α-bromoacetate, and α-bromonitrile proceeded efficiently in the presence of TMSCl and diisopropylamine. This reaction system was applied to the synthesis of an antispasmodic: butaverine.