Wu, Yingming Zhao, Jingfeng Chen, Jingbo Pan, Chengxue Li, Liang Zhang, Hongbin Enantioselective Sequential Conjugate Addition−Allylation Reactions: A Concise Total Synthesis of (+)-Podophyllotoxin A highly flexible and concise total synthesis of (+)-podophyllotoxin featured with an enantioselective sequential conjugate addition-allylation reaction was reported. Starting from commercially available 3,4,5-trimethoxycinnamic acid, this new route leads to (+)-podophyllotoxin <b>1</b> in only eight steps with 29% overall yield. Enantioselective;Sequential;conjugate;acid;enantioselective;sequential;synthesis;Podophyllotoxin;trimethoxycinnamic;Concise;podophyllotoxin;Conjugate;Synthesi 2009-02-05
    https://acs.figshare.com/articles/journal_contribution/Enantioselective_Sequential_Conjugate_Addition_Allylation_Reactions_A_Concise_Total_Synthesis_of_Podophyllotoxin/2880763
10.1021/ol8026208.s002