Total Synthesis of Pseudodehydrothyrsiferol HiokiHideaki MotosueMasatoshi MizutaniYasuhiko NodaAkira ShimodaTomoaki KuboMiwa HaradaKenichi FukuyamaYoshiyasu KodamaMitsuaki 2009 An enantioselective total synthesis of pseudodehydrothyrsiferol has been accomplished. The synthetic sequence highlights formation of the highly strained tetrahydropyran C-ring by a Mitsunobu-type S<sub>N</sub>2 reaction with an oxygen nucleophile.