10.1021/la900023p.s001
Sandy Budi Hartono
Sandy
Budi Hartono
Shi Zhang Qiao
Shi
Zhang Qiao
Kevin Jack
Kevin
Jack
Bradley P. Ladewig
Bradley P.
Ladewig
Zhengping Hao
Zhengping
Hao
Gao Qing (Max) Lu
Gao
Qing (Max) Lu
Improving Adsorbent Properties of Cage-like Ordered Amine Functionalized Mesoporous Silica with Very Large Pores for Bioadsorption
American Chemical Society
2009
XPS
adsorption capacity
MAS
Amine Functionalized Mesoporous Silica
BSA
APTES
FDU
pore mesoporous material
SAXS
TEM
amine organosilane
mesoporous silica
synthesis temperature domain
transmission electron microscopy
NMR
mesostructure
TGA
amine functionalized mesoporous silica
entrance size enlargement
hydrothermal treatment temperature
2009-06-02 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Improving_Adsorbent_Properties_of_Cage_like_Ordered_Amine_Functionalized_Mesoporous_Silica_with_Very_Large_Pores_for_Bioadsorption/2853388
In this paper, we report the successful synthesis of amine-functionalized FDU-12-type mesoporous silica with a very large pore (30.2 nm) and a highly ordered mesostructure by using 3-aminopropyltriethoxysilane (APTES) as an organosilane source. Small angle X-ray scattering (SAXS) and transmission electron microscopy (TEM) measurements confirmed that the materials possessed a face-centered cubic (space group <i>Fm</i>3<i>̅m</i>) mesostructure. Different techniques were used to obtain a significant pore and entrance size enlargement: low synthesis temperature and high hydrothermal treatment temperature. The amount of amine organosilane influenced the mesostructure of the mesoporous silica. It was found that the addition of inorganic salt (KCl) could help to maintain an ordered structure of the large pore mesoporous material. X-ray photoelectron spectroscopy (XPS), solid-state magic-angle spinning (MAS) <sup>13</sup>C nuclear magnetic resonance (NMR) and thermogravimetric analysis (TGA) verified the incorporation of amine functional groups on the surface of the materials. The addition of amine organosilane extended the synthesis temperature domain of ordered FDU-12 materials. The amine functional group significantly enhanced the adsorption capacity of the mesoporous materials, e.g., the amine functionalized mesoporous silica had 8-fold higher bovine serum albumin (BSA) adsorption capacity than that of the unfunctionalized one. It also had 2 times higher adsorption capacity for large cellulase enzymes. The amine functional group introduced positively charged groups on the surface of the mesoporous silica, which created strong electrostatic interactions between the protein and the silica.