10.1021/np900016h.s002
Daniel Anthony Dias
Daniel Anthony
Dias
David James Goble
David James
Goble
Claudio Andres Silva
Claudio Andres
Silva
Sylvia Urban
Sylvia
Urban
Phenylphenalenones from the Australian Plant <i>Haemodorum simplex</i>
American Chemical Society
2009
chemical shift reassignments
2 D NMR characterization
Australian Plant Haemodorum simplexChemical investigation
Australian plant Haemodorum simplex
dilatrin
compound
phenylphenalenone
isolation
cytotoxic activity
2009-06-26 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Phenylphenalenones_from_the_Australian_Plant_i_Haemodorum_simplex_i_/2847454
Chemical investigation of the Australian plant <i>Haemodorum simplex</i> resulted in the isolation of three new phenylphenalenones, haemodorone (<b>10</b>), haemodorol (<b>11</b>), and haemodorose (<b>12</b>), together with the previously reported compounds <b>5</b>, dilatrin (<b>6</b>), and xiphidone (<b>8</b>). The first complete 2D NMR characterization for all of the compounds isolated, including several chemical shift reassignments for dilatrin (<b>6</b>), is reported. In addition this is one of the few reports to discuss the isolation of new phenylphenalenones from an Australian medicinal plant. The crude extract of both the bulbaceous and aerial components of the plant exhibited varying degrees of antibacterial, antifungal, and antiviral activity, and only the bulbs displayed potent cytotoxic activity.