10.1021/ja9038505.s001 Gilbert Stork Gilbert Stork Ayako Yamashita Ayako Yamashita Julian Adams Julian Adams Gary R. Schulte Gary R. Schulte Richard Chesworth Richard Chesworth Yoji Miyazaki Yoji Miyazaki Jay J. Farmer Jay J. Farmer Regiospecific and Stereoselective Syntheses of (±) Morphine, Codeine, and Thebaine via a Highly Stereocontrolled Intramolecular 4 + 2 Cycloaddition Leading to a Phenanthrofuran System American Chemical Society 2009 Stereocontrolled Intramolecular 4 diene Regiospecific morphine alkaloids 2 Cycloaddition acid stereoselective formation methoxybenzofuran ester Phenanthrofuran SystemTotal syntheses Morphine Codeine Stereoselective Syntheses phenanthrofuran system intramolecular 4 2 cycloaddition Thebaine 2009-08-19 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Regiospecific_and_Stereoselective_Syntheses_of_Morphine_Codeine_and_Thebaine_via_a_Highly_Stereocontrolled_Intramolecular_4_2_Cycloaddition_Leading_to_a_Phenanthrofuran_System/2834536 Total syntheses of the morphine alkaloids are described that use a direct stereoselective formation of the phenanthrofuran system via an intramolecular 4 + 2 cycloaddition of a diene tethered to the 4-position of a 7-methoxybenzofuran-3-carboxylic acid ester.