10.1021/ja9038505.s001
Gilbert Stork
Gilbert
Stork
Ayako Yamashita
Ayako
Yamashita
Julian Adams
Julian
Adams
Gary R. Schulte
Gary R.
Schulte
Richard Chesworth
Richard
Chesworth
Yoji Miyazaki
Yoji
Miyazaki
Jay J. Farmer
Jay J.
Farmer
Regiospecific and Stereoselective Syntheses of (±) Morphine, Codeine, and Thebaine via a Highly Stereocontrolled Intramolecular 4 + 2 Cycloaddition Leading to a Phenanthrofuran System
American Chemical Society
2009
Stereocontrolled Intramolecular 4
diene
Regiospecific
morphine alkaloids
2 Cycloaddition
acid
stereoselective formation
methoxybenzofuran
ester
Phenanthrofuran SystemTotal syntheses
Morphine
Codeine
Stereoselective Syntheses
phenanthrofuran system
intramolecular 4
2 cycloaddition
Thebaine
2009-08-19 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Regiospecific_and_Stereoselective_Syntheses_of_Morphine_Codeine_and_Thebaine_via_a_Highly_Stereocontrolled_Intramolecular_4_2_Cycloaddition_Leading_to_a_Phenanthrofuran_System/2834536
Total syntheses of the morphine alkaloids are described that use a direct stereoselective formation of the phenanthrofuran system via an intramolecular 4 + 2 cycloaddition of a diene tethered to the 4-position of a 7-methoxybenzofuran-3-carboxylic acid ester.