Silver-Mediated Allylic Disulfide Rearrangement for Conjugation of Thiols in Protic Media
David Crich
Venkataraman Subramanian
Maheswaran Karatholuvhu
10.1021/jo902012m.s001
https://acs.figshare.com/articles/journal_contribution/Silver_Mediated_Allylic_Disulfide_Rearrangement_for_Conjugation_of_Thiols_in_Protic_Media/2805430
Alkyl and aryl allyl disulfides are induced to undergo the desulfurative allylic rearrangement by silver nitrate in protic solvents at room temperature, thereby removing the necessity for the use of phosphines as thiophilic reagents. The silver-mediated reaction functions at ambient temperature in protic solvents and in the absence of protecting groups
2009-12-18 00:00:00
Allylic
Conjugation
thiophilic
ambient
Disulfide
Thiol
aryl allyl disulfides
absence
phosphine
function
nitrate
necessity
Rearrangement
protic solvents
reagent
Protic
desulfurative allylic rearrangement
MediaAlkyl