Cobalt(II)-Catalyzed Intermolecular Benzylic C−H Amination with 2,2,2-Trichloroethoxycarbonyl Azide (TrocN<sub>3</sub>) Hongjian Lu Velusamy Subbarayan Jingran Tao X. Peter Zhang 10.1021/om900916g.s001 https://acs.figshare.com/articles/journal_contribution/Cobalt_II_Catalyzed_Intermolecular_Benzylic_C_H_Amination_with_2_2_2_Trichloroethoxycarbonyl_Azide_TrocN_sub_3_sub_/2797660 2,2,2-Trichloroethoxycarbonyl azide (TrocN<sub>3</sub>) is an effective nitrene source for cobalt(II)-catalyzed intermolecular nitrene insertion of C−H bonds. Among different metalloporphyrins studied, Co(II)(TPP) was shown to be a competent catalyst for the selective amination of various benzylic C−H bonds under mild conditions without the need of other reagents or additives, forming the desired Troc-protected amines in moderate to high yields with nitrogen gas as the only byproduct. 2010-01-25 00:00:00 Azide nitrene source cobalt metalloporphyrin additive azide Trichloroethoxycarbonyl Amination nitrogen gas byproduct Benzylic amines reagent nitrene insertion catalyst TrocN benzylic Co yield Cobalt amination Intermolecular bond