10.1021/jo9020776.s002 Tuan-jie Meng Tuan-jie Meng Yimin Hu Yimin Hu Shaowu Wang Shaowu Wang Efficient Construction of Five-Membered Aromatic and Nonaromatic Heterocycles from 1,6-Enynes by a Palladium-Catalyzed Domino Coupling/Cycloisomerization Process American Chemical Society 2010 Enyne Aromatic enyne aryl halides ProcessGeneral nonaromatic heterocycles method Nonaromatic Heterocycles construction formation substituent terminus Domino alkyne Efficient Construction 2010-02-05 00:00:00 Dataset https://acs.figshare.com/articles/dataset/Efficient_Construction_of_Five_Membered_Aromatic_and_Nonaromatic_Heterocycles_from_1_6_Enynes_by_a_Palladium_Catalyzed_Domino_Coupling_Cycloisomerization_Process/2793793 General and efficient methods for the construction of five-membered aromatic and nonaromatic heterocycles by palladium-catalyzed coupling/cycloisomerization of 1,6-enynes and aryl halides have been developed. Results indicate that substituents at the terminus of the alkynes have a significant effect on the selective formation of the products.