10.1021/jo902338w.s001
Steven M. Raders
Steven M.
Raders
Jesudoss V. Kingston
Jesudoss V.
Kingston
John G. Verkade
John G.
Verkade
Advantageous Use of <sup><i>t</i></sup>Bu<sub>2</sub>P-NP(<sup><i>i</i></sup>BuNCH<sub>2</sub>CH<sub>2</sub>)<sub>3</sub>N in the Hiyama Coupling of Aryl Bromides and Chlorides
American Chemical Society
2010
tBu 2P
0.5
High yields
Pd
Advantageou
biaryl
ChloridesAn
loading
variety
0.25
Aryl Bromides
Hiyama
aryl bromides
aryl chlorides
phenylsiloxane
mol
2010-03-05 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Advantageous_Use_of_sup_i_t_i_sup_Bu_sub_2_sub_P_N_P_sup_i_i_i_sup_BuNCH_sub_2_sub_CH_sub_2_sub_sub_3_sub_N_in_the_Hiyama_Coupling_of_Aryl_Bromides_and_Chlorides/2786425
An efficient catalytic route to biaryls by employing (generally) only 0.25 mol % of Pd(OAc)<sub>2</sub> and 0.5 mol % of <b>1</b> in the Hiyama coupling reaction is reported. High yields for electron-rich, -neutral, and -deficient aryl chlorides are obtained. A variety of phenylsiloxanes undergo coupling with aryl bromides and chlorides with low Pd(OAc)<sub>2</sub>/<b>1</b> loadings.