%0 Journal Article %A Fan, Meikun %A Thompson, Matthew %A Andrade, Maria Luiza %A Brolo, Alexandre G. %D 2010 %T Silver Nanoparticles on a Plastic Platform for Localized Surface Plasmon Resonance Biosensing %U https://acs.figshare.com/articles/journal_contribution/Silver_Nanoparticles_on_a_Plastic_Platform_for_Localized_Surface_Plasmon_Resonance_Biosensing/2747467 %R 10.1021/ac101495m.s001 %2 https://ndownloader.figshare.com/files/4427611 %K surface plasmon resonance %K SNOPS strip %K sensor strips %K Localized Surface Plasmon Resonance BiosensingA %K protein adsorption %K Ag NPs %K Silver Nanoparticles %K 500 nM %K LSPR biosensor %K Plastic Platform %K fabrication method %K polyethylene terephthalate %X A cost-effective fabrication method for the preparation of localized surface plasmon resonance (LSPR) biosensors supported on plastics is described. The silver-nanoparticles-on-plastic sensor (SNOPS) was fabricated by chemically modifying the surface of a common plastic, polyethylene terephthalate (PET) to allow the efficient immobilization of Ag NPs. The LSPR of the SNOPS strip showed good sample-to-sample reproducibility. The analytical performance of the sensor strips for monitoring both thiol and protein adsorption, including bioaffinity, was examined. The limit of quantification to the adsorption of 11-mercaptoundecanoic acid was 500 nM and for the detection of streptavidin was ∼9.5 nM. SNOPS can then be used as a cheap, versatile, and yet sensitive LSPR biosensor. %I ACS Publications