Silver Nanoparticles on a Plastic Platform for Localized Surface Plasmon Resonance Biosensing Meikun Fan Matthew Thompson Maria Luiza Andrade Alexandre G. Brolo 10.1021/ac101495m.s001 https://acs.figshare.com/articles/journal_contribution/Silver_Nanoparticles_on_a_Plastic_Platform_for_Localized_Surface_Plasmon_Resonance_Biosensing/2747467 A cost-effective fabrication method for the preparation of localized surface plasmon resonance (LSPR) biosensors supported on plastics is described. The silver-nanoparticles-on-plastic sensor (SNOPS) was fabricated by chemically modifying the surface of a common plastic, polyethylene terephthalate (PET) to allow the efficient immobilization of Ag NPs. The LSPR of the SNOPS strip showed good sample-to-sample reproducibility. The analytical performance of the sensor strips for monitoring both thiol and protein adsorption, including bioaffinity, was examined. The limit of quantification to the adsorption of 11-mercaptoundecanoic acid was 500 nM and for the detection of streptavidin was ∼9.5 nM. SNOPS can then be used as a cheap, versatile, and yet sensitive LSPR biosensor. 2010-08-01 00:00:00 surface plasmon resonance SNOPS strip sensor strips Localized Surface Plasmon Resonance BiosensingA protein adsorption Ag NPs Silver Nanoparticles 500 nM LSPR biosensor Plastic Platform fabrication method polyethylene terephthalate