10.1021/ac101495m.s001
Meikun Fan
Meikun
Fan
Matthew Thompson
Matthew
Thompson
Maria Luiza Andrade
Maria Luiza
Andrade
Alexandre G. Brolo
Alexandre G.
Brolo
Silver Nanoparticles on a Plastic Platform for Localized Surface Plasmon Resonance Biosensing
American Chemical Society
2010
surface plasmon resonance
SNOPS strip
sensor strips
Localized Surface Plasmon Resonance BiosensingA
protein adsorption
Ag NPs
Silver Nanoparticles
500 nM
LSPR biosensor
Plastic Platform
fabrication method
polyethylene terephthalate
2010-08-01 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Silver_Nanoparticles_on_a_Plastic_Platform_for_Localized_Surface_Plasmon_Resonance_Biosensing/2747467
A cost-effective fabrication method for the preparation of localized surface plasmon resonance (LSPR) biosensors supported on plastics is described. The silver-nanoparticles-on-plastic sensor (SNOPS) was fabricated by chemically modifying the surface of a common plastic, polyethylene terephthalate (PET) to allow the efficient immobilization of Ag NPs. The LSPR of the SNOPS strip showed good sample-to-sample reproducibility. The analytical performance of the sensor strips for monitoring both thiol and protein adsorption, including bioaffinity, was examined. The limit of quantification to the adsorption of 11-mercaptoundecanoic acid was 500 nM and for the detection of streptavidin was ∼9.5 nM. SNOPS can then be used as a cheap, versatile, and yet sensitive LSPR biosensor.