10.1021/ol101611v.s003
Peizhong Xie
Peizhong
Xie
You Huang
You
Huang
Ruyu Chen
Ruyu
Chen
Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Synthesis of <i>trans</i>-2,3-Dihydrobenzofurans from Salicyl <i>N</i>-Thiophosphinyl Imines and Allylic Carbonates
American Chemical Society
2010
skeleton
domino
Imine
Stereoselective Synthesis
Allylic Carbonates
Salicyl
imine
diastereoselectivity
approach
dipolar
salicyl
method
synthon
allylic carbonates
kind
Domino
tran
allylic carbonate
construction
2010-09-03 00:00:00
Dataset
https://acs.figshare.com/articles/dataset/Phosphine_Catalyzed_Domino_Reaction_Highly_Stereoselective_Synthesis_of_i_trans_i_2_3_Dihydrobenzofurans_from_Salicyl_i_N_i_Thiophosphinyl_Imines_and_Allylic_Carbonates/2735920
A novel phosphine-catalyzed domino reaction of salicyl <i>N</i>-thiophosphinyl imines and allylic carbonates was developed. The allylic carbonate, in this reaction, serves as a new kind of 1,1-dipolar synthon. This method offered a powerful approach to the construction of a highly substituted <i>trans</i>-2,3-dihydrobenzofuran skeleton with high diastereoselectivity.