10.1021/ja108073k.s001 Liangbin Huang Liangbin Huang Huanfeng Jiang Huanfeng Jiang Chaorong Qi Chaorong Qi Xiaohang Liu Xiaohang Liu Copper-Catalyzed Intermolecular Oxidative [3 + 2] Cycloaddition between Alkenes and Anhydrides: A New Synthetic Approach to γ-Lactones American Chemical Society 2010 New Approach cycloaddition Anhydride Alkene substrate scope cyclization process Oxidative lactone anhydride alkene oxidant oxidative yield LactonesA Cycloaddition Intermolecular 2010-12-22 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Copper_Catalyzed_Intermolecular_Oxidative_3_2_Cycloaddition_between_Alkenes_and_Anhydrides_A_New_Synthetic_Approach_to_Lactones/2703148 A new copper-catalyzed oxidative [3 + 2] cycloaddition of alkenes with anhydrides using oxygen as the sole oxidant to afford γ-lactones has been developed. This catalyzed cyclization process has a broad substrate scope and affords γ-lactones in good to excellent yields.