Eccles, Kevin S. Deasy, Rebecca E. Fábián, László Maguire, Anita R. Lawrence, Simon E. The Use of Co-crystals for the Determination of Absolute Stereochemistry: An Alternative to Salt Formation Absolute stereochemistry of oils and viscous liquids can be difficult to determine. Co-crystallization involves generating a crystalline material consisting of more than one neutral compound. The combination of co-crystallization with both X-ray diffraction and chiral HPLC was particularly powerful in overcoming these difficulties for a series of chiral 3-arylbutanoic acids. Co-crystallization offers advantages over salt formation because co-crystals dissociate in solution, meaning identical HPLC conditions can be used for both the materials of interest and their co-crystals. series;acid;Salt FormationAbsolute stereochemistry;HPLC conditions;chiral HPLC;Determination;salt formation;arylbutanoic;combination;material;solution;difficulty;meaning;compound;diffraction;Absolute Stereochemistry;Alternative 2011-02-18
    https://acs.figshare.com/articles/dataset/The_Use_of_Co_crystals_for_the_Determination_of_Absolute_Stereochemistry_An_Alternative_to_Salt_Formation/2690677
10.1021/jo102148p.s006