10.1021/ol200047v.s001
Christian Abbet
Christian
Abbet
Markus Neuburger
Markus
Neuburger
Trixie Wagner
Trixie
Wagner
Melanie Quitschau
Melanie
Quitschau
Matthias Hamburger
Matthias
Hamburger
Olivier Potterat
Olivier
Potterat
Phyteumosides A and B: New Saponins with Unique Triterpenoid Aglycons from <i>Phyteuma orbiculare</i> L.
American Chemical Society
2011
Unique Triterpenoid Aglycons
Compound 2
Phyteuma orbiculare
oxygen bridges
gammaceroid triterpene
triterpenoid aglycons
Phyteuma orbiculare L.Phyteumosides
cyclized onoceroid
tetrahydropyran rings
New Saponins
chemical methods
2011-03-18 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Phyteumosides_A_and_B_New_Saponins_with_Unique_Triterpenoid_Aglycons_from_i_Phyteuma_orbiculare_i_L_/2681962
Phyteumosides A (<b>1</b>) and B (<b>2</b>), two saponins with unprecedented triterpenoid aglycons, were isolated from the aerial parts of <i>Phyteuma orbiculare</i> (Campanulaceae). Their structures were elucidated by spectroscopic and chemical methods and corroborated by X-ray diffraction analyses of the aglycons obtained through enzymatic hydrolysis. The aglycon of <b>1</b> can be considered as an incompletely cyclized onoceroid or gammaceroid triterpene with two additional tetrahydropyran rings arising from oxygen bridges. Compound <b>2</b> possesses a new 17-polypodene aglycon.