Intermolecular Atom Transfer Radical Addition to Olefins Mediated by Oxidative Quenching of Photoredox Catalysts
John D. Nguyen
Joseph W. Tucker
Marlena D. Konieczynska
Corey R. J. Stephenson
10.1021/ja108560e.s001
https://acs.figshare.com/articles/journal_contribution/Intermolecular_Atom_Transfer_Radical_Addition_to_Olefins_Mediated_by_Oxidative_Quenching_of_Photoredox_Catalysts/2675287
Atom transfer radical addition of haloalkanes and α-halocarbonyls to olefins is efficiently performed with the photocatalyst Ir[(dF(CF<sub>3</sub>)ppy)<sub>2</sub>(dtbbpy)]PF<sub>6</sub>. This protocol is characterized by excellent yields, mild conditions, low catalyst loading, and broad scope. In addition, the atom transfer protocol can be used to quickly and efficiently introduce vinyl trifluoromethyl groups to olefins and access 1,1-cyclopropane diesters.
2011-03-30 00:00:00
Ir
vinyl trifluoromethyl groups
halocarbonyl
atom transfer protocol
olefins
access
scope
photocatalyst
Intermolecular Atom Transfer Radical Addition
cyclopropane
haloalkane
diester
Olefins Mediated
Oxidative Quenching
catalyst loading
yield
Photoredox CatalystsAtom transfer