TY - DATA T1 - GL261-injected WT mice (solid line) and C57BL/6 TCR-δ-/- mice (B6.129P2-TCR-δtm1Mom/J) (dashed line) received intracranial injections of 5.0 x 105 GL261 cells and were monitored for survival. PY - 2015/05/08 AU - Benjamin H. Beck AU - Hyunggoon Kim AU - Rebecca O’Brien AU - Martin R. Jadus AU - G. Yancey Gillespie AU - Gretchen A. Cloud AU - Neil T. Hoa AU - Catherine P. Langford AU - Richard D. Lopez AU - Lualhati E. Harkins AU - Lawrence S. Lamb Jr. UR - https://plos.figshare.com/articles/figure/GL261_injected_WT_mice_solid_line_and_C57BL_6_TCR_sup_sup_mice_B6_129P2_TCR_sup_tm1Mom_sup_J_dashed_line_received_intracranial_injections_of_5_0_x_10_sup_5_sup_GL261_cells_and_were_monitored_for_survival_/2667550 DO - 10.1371/journal.pone.0122387.g005 L4 - https://ndownloader.figshare.com/files/4329934 KW - Circulating γδ T cells transiently KW - WT mice KW - syngeneic WT C 57BL mice KW - NKG 2D ligands expression KW - IFN KW - TCR KW - tumor growth inhibition KW - GL 261 intracranial gliomas KW - T cell receptor repertoire KW - upregulated Annexin V expression KW - γδ T cells 15 m KW - immunocompetent mouse model KW - V δ1 subsets KW - γδ T cell expansion KW - γδ T cells KW - syngeneic GL 261 gliomas KW - V δ4 population KW - T cell invasion KW - glioma cell lines KW - Immunocompetent Mouse Model KW - γδ T cell count KW - IL KW - end stage N2 - Median survival for TCRδ-/- mice was no different than WT, showing that the absence of γδ T cells does not significantly effect survival. ER -