Li, Wei Liu, Xiaohua Hao, Xiaoyu Hu, Xiaolei Chu, Yangyang Cao, Weidi Qin, Song Hu, Changwei Lin, Lili Feng, Xiaoming New Electrophilic Addition of α-Diazoesters with Ketones for Enantioselective C–N Bond Formation α-Diazoesters were discovered to be good electrophiles in a catalytic asymmetric α-functionalization of ketones for the first time. This reaction also provided a direct and efficient method for C–N bond formation with excellent yields (up to 98%) and enantioselectivities (up to 99% ee) under mild conditions. The application of the electrophilicity of α-diazoesters opens up a novel way to access the diversity of diazo chemistry. Enantioselective;diazo chemistry;Diazoester;application;access;ee;Formation;functionalization;method;enantioselectivitie;electrophile;diversity;diazoester;New Electrophilic Addition;Ketone;formation;novel way;Bond;yield;ketone;electrophilicity;bond 2011-10-05
    https://acs.figshare.com/articles/journal_contribution/New_Electrophilic_Addition_of_Diazoesters_with_Ketones_for_Enantioselective_C_N_Bond_Formation/2607490
10.1021/ja2056159.s002