TY - DATA T1 - Tandem Reactions of 1,2-Allenic Ketones Leading to Substituted Benzenes and α,β-Unsaturated Nitriles PY - 2011/10/07 AU - Xinying Zhang AU - Xuefei Jia AU - Liangliang Fang AU - Nan Liu AU - Jianji Wang AU - Xuesen Fan UR - https://acs.figshare.com/articles/journal_contribution/Tandem_Reactions_of_1_2_Allenic_Ketones_Leading_to_Substituted_Benzenes_and_Unsaturated_Nitriles/2605462 DO - 10.1021/ol201789z.s001 L4 - https://ndownloader.figshare.com/files/4254808 KW - allenic KW - tandem Reactions KW - functionalized benzenes KW - approach KW - reaction proceeds KW - Ketone KW - nitrile KW - cyanoacetate KW - tandem process KW - Substituted Benzenes KW - ketone KW - Allenic KW - aldol KW - Unsaturated N2 - One-pot double Michael addition/intramolecular aldol reaction/decarboxylation of 1,2-allenic ketones with cyanoacetate offers an efficient and convenient approach to highly functionalized benzenes. With 2-substituted cyanoacetates, the reaction proceeds via a different tandem process to afford α,β-unsaturated nitriles effectively. ER -