10.1371/journal.pone.0043646.g001
Atsushi Shiozaki
Atsushi
Shiozaki
Grace Shen-Tu
Grace
Shen-Tu
Xiaohui Bai
Xiaohui
Bai
Daisuke Iitaka
Daisuke
Iitaka
Valentina De Falco
Valentina
De Falco
Massimo Santoro
Massimo
Santoro
Shaf Keshavjee
Shaf
Keshavjee
Mingyao Liu
Mingyao
Liu
XB130 controls cell cycle progression of cancer cells.
Public Library of Science
2012
controls
progression
cancer
2012-08-23 02:14:09
Figure
https://plos.figshare.com/articles/figure/_XB130_controls_cell_cycle_progression_of_cancer_cells_/258049
<p>(A and B) Down-regulation of XB130 inhibited G<sub>1</sub>-S phase progression in WRO and A549 cells. Cells transfected with control or XB130 siRNA were stained with PI and analyzed by flow cytometry. Mean ± SEM. <i>n</i> = 6. *<i>p</i><0.05 (compared with control siRNA). (C) Reduced Ki67 and PCNA levels in XB130 siRNA treated WRO and A549 cells, as determined by western blotting. <i>n</i> = 3. *<i>p</i><0.05 (compared with control siRNA treated group). (D) Presence of RET/PTC rearrangement was confirmed in both TPC-1 and WRO cells using RT-PCR. A549 cells do not contain RET/PTC rearrangement.</p>