Forest plots for association between VKORC1 rs9934438 and stable dose. Andrea L. Jorgensen Richard J. FitzGerald James Oyee Munir Pirmohamed Paula R. Williamson 10.1371/journal.pone.0044064.g005 https://plos.figshare.com/articles/figure/_Forest_plots_for_association_between_VKORC1_rs9934438_and_stable_dose_/255471 <p>Effect estimates are differences in means and 95% confidence intervals. ¶: Ethnicity of patients is unclear, although likely to be predominantly White so included in sensitivity analysis of White ethnic group. §: Paper does not mention genotype quality control procedures, so reliability uncertain.†: Paper does not mention tests for population stratification, which is of concern since more than one ethnic group included.‡: Paper does not mention assessing compliance with treatment. ¥: Studies reported results assuming a dominant mode of inheritance. The effect size estimated is therefore for heterozygotes and mutant-type homozygotes combined versus wild-type homozygotes.</p> 2013-02-20 00:13:09 plots vkorc1 rs9934438