%0 Journal Article %A Dai, Chao %A Xu, Zhaoqing %A Huang, Fei %A Yu, Zhengkun %A Gao, Yan-Feng %D 2016 %T Lewis Acid-Catalyzed, Copper(II)-Mediated Synthesis of Heteroaryl Thioethers under Base-Free Conditions %U https://acs.figshare.com/articles/journal_contribution/Lewis_Acid_Catalyzed_Copper_II_Mediated_Synthesis_of_Heteroaryl_Thioethers_under_Base_Free_Conditions/2525200 %R 10.1021/jo202624s.s001 %2 https://ndownloader.figshare.com/files/4168195 %K Heteroaryl Thioethers %K ConditionsA %K heteroarene %K acid %K heterocyclic methyl thioethers %K synthesis %K Synthesi %K FeII %K NiII %K methylthiolation reagent %K AgI %K Lewis %K DMSO %X A Lewis acid (AgI, NiII, or FeII) catalyzed, CuII-mediated thiolation reaction between heteroarenes and thiols was achieved with good yield under base-free conditions. DMSO could serve as an effective methylthiolation reagent for the synthesis of heterocyclic methyl thioethers. %I ACS Publications