Lewis Acid-Catalyzed,
Copper(II)-Mediated Synthesis
of Heteroaryl Thioethers under Base-Free Conditions
Chao Dai
Zhaoqing Xu
Fei Huang
Zhengkun Yu
Yan-Feng Gao
10.1021/jo202624s.s001
https://acs.figshare.com/articles/journal_contribution/Lewis_Acid_Catalyzed_Copper_II_Mediated_Synthesis_of_Heteroaryl_Thioethers_under_Base_Free_Conditions/2525200
A Lewis acid (Ag<sup>I</sup>, Ni<sup>II</sup>, or Fe<sup>II</sup>) catalyzed, Cu<sup>II</sup>-mediated thiolation reaction
between
heteroarenes and thiols was achieved with good yield under base-free
conditions. DMSO could serve as an effective methylthiolation reagent
for the synthesis of heterocyclic methyl thioethers.
2016-02-21 12:32:47
Heteroaryl Thioethers
ConditionsA
heteroarene
acid
heterocyclic methyl thioethers
synthesis
Synthesi
FeII
NiII
methylthiolation reagent
AgI
Lewis
DMSO