Wharton-Fragmentation-Based Approach to the Carbocyclic Core of the Phomoidrides MurphyGraham K. HamaNaoto BedermannAaron DongPing SchneiderChris M. McMahonTravis C. TaoRan N. TwenterBarry M. SpiegelDavid A. WoodJohn L. 2012 The carbocyclic core of the phomoidrides has been synthesized efficiently and in high yield. Key steps include a phenolic oxidation/intramolecular Diels–Alder sequence, tandem radical cyclization, and a late-stage Wharton fragmentation of a densely functionalized isotwistane skeleton.